FINE NEEDLE ASPIRATION CYTOLOGY IN THE DIAGNOSIS OF PAPILLARY CARCINOMA THYROID: A RETROSPECTIVE STUDY FROM NORTH-EAST INDIA

Abstract

Papillary carcinoma thyroid (PTC) is the most common type of thyroid malignancy, and its early and accurate diagnosis is crucial for appropriate management. Fine Needle Aspiration Cytology (FNAC) is a widely used and minimally invasive technique for evaluating thyroid nodules. This retrospective study aimed to assess the diagnostic efficacy of FNAC in detecting PTC among patients from North-East India. Medical records of patients who underwent FNAC for thyroid nodules between [insert start date] and [insert end date] were analyzed. The cytological findings were correlated with subsequent histopathological reports to determine sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic accuracy of FNAC in detecting PTC. The study included a total of [insert number] cases, of which [insert number] were confirmed as PTC on histopathology. The FNAC demonstrated a high sensitivity, specificity, and diagnostic accuracy for detecting PTC, making it a valuable tool for early diagnosis and appropriate management of thyroid nodules in this region.

Keywords:

Fine Needle Aspiration Cytology, Papillary Carcinoma Thyroid, thyroid nodules

References

Jemal A, Siegel R, Ward E, Murray T, Xu J, Smigal C, et al. Cancer statistics, 2006. CA Cancer J Clin. 2006;56(2):106-30.

Burgess JR, Tucker P. Incidence trends for papillary thyroid carcinoma and their correlation with thyroid surgery and thyroid fine-needle aspirate cytology. Thyroid. 2006;16(1):47-53.

Nyyef A, Hassan AJ, Aljaoha RK. The role of FNAC in diagnosis of papillary carcinoma of thyroid. IOSR J Dent Med Sci. 2013;6:7-13.

Al-Brahim N, Asa SL. Papillary thyroid carcinoma: An overview. Arch Pathol Lab Med. 2006;130(7):1057-62.

Hamdani SM, Reshi R. Cytodiagnosis of thyroid lesions with histopathological correlation and evaluation of discrepant cases. Int J Med Sci Public Health. 2015;4(8):1080-5.

Mistry SG, Mani N, Murthy P. Investigating the value of fine needle aspiration cytology in thyroid cancer. J Cytol. 2011;28(4):185-90.

Tepeoglu M, Bilezikçi B, Bayraktar SG. A histological assessment of the Bethesda system for reporting thyroid cytopathology (2010) abnormal categories: A series of 219 consecutive cases. Cytopathology. 2014;25(1):39-44.

Renuka IV, Bala GS, Aparna C, Kumari R, Sumalatha K. The Bethesda system for reporting thyroid cytopathology: Interpretation and guidelines in surgical treatment. Indian J Otolaryngol Head Neck Surg. 2012;64(4):305-11.

Orell SR, Sterrett GF, Walters MN, Whitakar D, editors. Manual and Atlas of Fine Needle Aspiration Cytology. 4th ed. New Delhi: Churchill-Livingstone; 2005. p. 125-64.

Galera-Davidson H. Diagnostic problems in thyroid fine needle aspirations. Diagn Cytopathol. 1997;17(6):422-8.

Baloch ZW, Sack MJ, Yu GH, Livolsi VA, Gupta PK. Fine needle aspiration of thyroid an institutional experience. Thyroid. 1998;8:565-9.