MOLECULAR INSIGHTS INTO THE REPLICATION AND PATHOGENESIS OF HEPATITIS C VIRUS

Ali Hassanen Ali

doi:10.55640/ijmsdh-10-11-05

Open Access

MOLECULAR INSIGHTS INTO THE REPLICATION AND PATHOGENESIS OF HEPATITIS C VIRUS

Vol. 10 No. 11 (2024): Volume 10 Issue 11 | Pages: 49-62 | https://doi.org/10.55640/ijmsdh-10-11-05

Authors

Ali Hassanen Ali
National Center of Hematology, Mustansiriyah University, Baghdad, Iraq.

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Published Date: 2024-11-13
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This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors retain the rights to their work published in the International Journal of Medical Science and Dental Health and may republish or reproduce their own work, provided proper citation to the original publication in IJMSDH is included.

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MOLECULAR INSIGHTS INTO THE REPLICATION AND PATHOGENESIS OF HEPATITIS C VIRUS. (2024). International Journal of Medical Science and Dental Health, 10(11), 49-62. https://doi.org/10.55640/ijmsdh-10-11-05

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Abstract

Hepatitis C virus (HCV) is a major infectious disease problem worldwide, resulting in serious liver disease, including cirrhosis and hepatocellular carcinoma. This review article acts as a general overview of molecular aspects of HCV replication and pathogenesis emphasizing the virus structure and genome, entry mechanisms, the replication cycle, and HCV interactions with the host immune system. It also examines the progression of disease causing HCV infections and the clinical symptoms. Antiviral treatments have improved patient outcomes, but they remain far from an effective vaccine, because viral diversity, lack of access to health care, remain. Research in the future should look to increase healthcare accessibility, to understand long term outcomes after treatment, and to develop the vaccine. Solution to these challenges will enable us to diminish the worldwide burden of HCV and better patient health results.

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