Detection of Human T-cell Leukemia Virus Type 1 in adult T- cell Leukemia by RT-qPCR

Abstract

Human T-cell Leukemia Virus Type 1 (HTLV-1) is a retrovirus associated with serious hematological and neurological disorders. Understanding its epidemiological distribution is essential for effective prevention and control strategies. Human samples from Leukemia patients were collected from November 16, 2024, to January 1, 2025. The age range of the patients was 18 years to 80 years.  The RT-qPCR method was used to detect Human T-cell Leukemia Virus Type 1  in all samples; the results showed Twenty-five positive cases for Human T-cell Leukemia Virus Type 1 . The population groups studied were divided into five age groups: 18-27, 28-37, 38-47, 48-57, and 58-67 years. The first group (18-27) had the highest number of infected cases at 56%, compared to the age group (28-37 at 12%, 38-47 at 8%, 48-57 at 14%, and the age group 58-67 at 8%).  The samples were collected from Hospital, Middle Euphrates Cancer Center in Najaf province. The findings revealed that individuals aged 18 to 27 years had the highest infection rate with Human T-cell Leukemia Virus Type 1 (HTLV-1). Additionally, the infection was more prevalent among males compared to females.Leukemia.

Keywords:

Leukemia, Human T-cell Leukemia Virus Type 1, RT-qPCR

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