Role of Tetracycline as Antibiotic Adjunctive Therapy in Local Delivery of Treatment Periodontitis

Abstract

Most of the individuals affected by “periodontitis: had a good response to the mechanical debridement for achieving long success. The adjuncts' use may be essential in cases that had no response to treatment, especially when surgical opportunities not feasible.

Objective: to determine tetracycline's impact on Probing Pocket Depth (PPD), Plaque Index (PI), Bleeding On Probing (BOP), and Clinical Attachment Level (CAL) over a six-month follow-up period.

Method: Thirty participants diagnosed in chronic Periodontitis and selected in random assignment into two- groups: scaling and root planning (SRP) with local delivery of tetracycline (test) or SRP alone (control). The parameters, included Probing Pocket Depth (PPD), Clinical Attachment Level (CAL), Plaque Index (PI), and Bleeding on Probing (BOP), were recorded at beginning, 1, 3, and 6 months.

Result: at six months, the SRP + tetracycline group showed significant decrease in PPD, BOP, and greater CAL gain in compared with that in SRP only (p < 0.05).

Conclusion: A local deliver of Tetracycline, regarded as an adjunct to SRP, with a significant improvement of the clinical outcomes in the periodontitis in compared with SRP alone.

Keywords:

Tetracycline, bleeding on probing, tetracycline, plaque index

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